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Our Capabilities / Strengths 

Our Scientists

Sateesh Apté, MD

Dr. Apté is the founder and CEO of ImmunoScience, Inc., in his capacity as the Managing Director of Swiss Pacific Group, Ltd. For his extensive research in the field of HIV/AIDS, Dr. Apté has been awarded several patents for the therapeutic vaccines, with other patents pending in the United States and internationally for an HIV vaccine, Cancer vaccines and saliva-based diagnostic tests. Dr. Apté received his undergraduate medical education in India followed by his graduate fellowships and residencies at Haffkine Institue collaborating with the Pasteur Institute, Clinical and Research fellowships at Harvard Medical School and Harvard teaching hospitals as well as senior fellowship at Stanford University Medical Center. Dr. Apté is a board qualified neurologist with a special interest in neuroendocrinology and is licensed to practice medicine in California. Dr. Apté has acted as a consultant for both The National Multiple Sclerosis Society and the Epilepsy League of American since 1991, and has authored and co-authored numerous publications.

Victor Martin, PhD

Dr. Martin is the Vice President of Manufacturing and Regulatory Affairs at ImmunoScience. With the company since 1996, his research and development of saliva-based testing has been monumental. Dr. Martin has extensive experience in biotechnology and clinical industries, as well as substantial work in product development, quality assurance and product optimization. Dr. Martin earned his Ph.D. in Chemical Pathology/Clinical Chemistry at St. Bartholomew's Hospital Medical School, University of London, London, UK and a B.Sc. (Honours) in Chemistry at Queen Mary College, University of London, London, UK. His continuing professional studies include the Robert Spivok Associates GMP Seminar, Total Quality Management Studies at University of California, Berkeley and Project Management at University of California, Berkeley.

In addition to these, ImmunoScience has several research and associate scientists and biotechnologists that complement the team.

Our Capabilities

ImmunoScience, with its fully equipped BSL-2 and BSL-3 facilities has established very good expertise/competence in the following areas:
  • Assay design
  • Assay development, Product Development and assay optimization for rapid diagnostics devices for antibody and antigen capture assays
  • Bacterial preparation
  • Biostatistical analysis
  • BSL 2 certified scientists
  • BSL-3 certified scientists
  • BSL-2 Laboratory design and implementation
  • BSL-3 Laboratory design and implementation
  • Cellular fractionation and purification
  • Colloidal Gold conjugate production for Rapid diagnostics
  • Diafiltration.
  • Direct-Flow Filtration
  • DNA and RNA Viral particle purification
  • DNA and RNA virus cultivation and harvesting
  • Expertise at recombinant DNA/molecular biology techniques
  • Expertise in the field of HIV-1 viral assembly and genomic RNA
  • Extensive cell culture expertise, including viral infections, transductions and transfections FACS
  • Fluorescence and confocal microscopy
  • Gel Exclusion chromatography
  • GLP and GMP quality control expertise for regulatory compliance documentation
  • Handling of clinical laboratory specimens
  • Handling of infectious materials
  • Handling of radioactive materials
  • His-Tag technology
  • Immuno-blotting to quantitate protein levels in cells and tissues.
  • Immunoprecipitation
  • In-vitro transcription of viral RNAs
  • Large scale viral panel production
  • Live cell vitrification
  • Magnetic cell separation
  • Manipulation and characterization of RNA, DNA, and proteins, recombinant DNA technology, sequencing and sequence analysis
  • Molecular cloning
  • Monoclonal and polyclonal antibody production
  • Northern/Southern blotting of RNA/DNA.
  • optimization of downstream purification processes
  • optimization of upstream production processes
  • PCR
  • Plasmid and siRNA transfections
  • Plasmid manipulations such as subcloning
  • Polyclonal and Monoclonal cell isolation
  • Preparation of small molecule conjugates for antibody production
  • Pulse chase assays
  • Purification and identification of various peptides and proteins using Affinity Chromatography
  • Purification and preparation of antigens for various disease states using bacterial cell culture techniques
  • Real time PCR
  • Scientific writing
  • Semi-quantitative RT-PCR, quantitative-PCR (qPCR) and RNase-protection assays for quantifying gene expression
  • shRNA applications
  • siRNA applications
  • Site-directed mutagenesis
  • Tangential-Flow Filtration,
  • TCID50 Assays
  • Tissue culture
  • Viral vector design and production
  • Western Blotting